Anixa Biosciences Announces Japanese Patent on Ovarian Cancer Vaccine
Preclinical work for the prophylactic vaccine, invented and developed at Cleveland Clinic, is ongoing with support from the National Cancer Institute's PREVENT Program
SAN JOSE, Calif., Jan. 25, 2022 /PRNewswire/ -- Anixa Biosciences, Inc. (NASDAQ: ANIX), a biotechnology company focused on the treatment and prevention of cancer and infectious diseases, today announced that the Japanese Patent Office has issued a Decision to Grant of a patent to Cleveland Clinic titled, "Ovarian Cancer Vaccines." The technology was invented by Drs. Vincent K. Tuohy, Suparna Mazumder and Justin M. Johnson at Cleveland Clinic. Anixa is the worldwide licensee for the vaccine technology. Patents for the technology were issued in the U.S. and Europe in 2021.
"We're pleased to announce this additional intellectual property protection of Anixa's novel ovarian cancer vaccine, which was developed at Cleveland Clinic and is being studied at NCI. This unique technology has the potential to be the first vaccine to prevent ovarian cancer, which remains one of the most devastating and difficult-to-treat cancers," said Dr. Amit Kumar, CEO, President and Chairman of Anixa Biosciences. "If successful, this vaccine could prevent ovarian cancer from ever occurring and spare patients from undergoing chemotherapy and extensive surgical treatments, and potentially save lives. We look forward to continuing our preclinical work in the hope that this vaccine will add to the arsenal needed to target this challenging cancer and ultimately make a difference for many patients."
The ovarian cancer vaccine targets the extracellular domain of anti-Müllerian hormone receptor 2 (AMHR2-ED), which is expressed in the ovaries but disappears as a woman reaches and advances through menopause. Of note, the majority of ovarian cancer diagnoses occur after menopause, and AMHR2-ED is expressed again in the majority of ovarian cancers. By receiving a vaccine such as Anixa's that targets AMHR2-ED after reaching menopause, ovarian cancer, historically one of the most aggressive gynecological cancers, could be prevented from ever developing.
Preclinical work to advance the vaccine is ongoing through the PREVENT Program at the National Cancer Institute (NCI), which supports preclinical innovative interventions and biomarkers for cancer prevention and interception. Preclinical data published in Cancer Prevention Research in 2017 supports ongoing advancement toward clinical studies.
About Anixa Biosciences, Inc.
Anixa is a publicly-traded
biotechnology company developing a number of programs addressing cancer
and infectious disease. Anixa's therapeutics portfolio includes a cancer
immunotherapy program which uses a novel type of CAR-T, known as
chimeric endocrine receptor T-cell (CER-T) technology, and a COVID-19
therapeutics program focused on inhibiting certain viral protein
function. The company's vaccine portfolio includes a vaccine to prevent
breast cancer – specifically triple negative breast cancer (TNBC), the
most lethal form of the disease – and a vaccine to prevent ovarian
cancer. These vaccine technologies focus on immunizing against specific
proteins that have been found to be expressed in certain forms of
cancer. Anixa continually examines emerging technologies in
complementary fields for further development and commercialization.
Additional information is available at www.anixa.com.
Forward-Looking Statements
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Forward-looking statements are not statements of historical facts, but
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including those concerning our expectations, involve risks,
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which may cause our actual results, performance or achievements, or
industry results, to be materially different from any future results,
performance, or achievements expressed or implied by such
forward-looking statements. These risks, uncertainties and factors
include, but are not limited to, those factors set forth in "Item 1A -
Risk Factors" and other sections of our most recent Annual Report on
Form 10-K as well as in our Quarterly Reports on Form 10-Q and Current
Reports on Form 8-K. We undertake no obligation to publicly update or
revise any forward-looking statements, whether as a result of new
information, future events or otherwise, except as required by law. You
are cautioned not to unduly rely on such forward-looking statements when
evaluating the information presented in this press release.
Contacts
Company Contact:
Mike Catelani
Chief Operating Officer and Chief Financial Officer
mcatelani@anixa.com
408-708-9808
Media:
Slavena Salve Nissan, M.D.
LifeSci Communications
snissan@lifescicomms.com
718-483-4440
Investors:
Eric Ribner
LifeSci Advisors, LLC
eric@lifesciadvisors.com
646-751-4363
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SOURCE Anixa Biosciences, Inc.