KMPH Quick Facts---August, 2021

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2. KemPharm Partnered Assets — Potential for Near and Long - Term Value KemPharm Current Development Pipeline Recent News  KemPharm Announces U.S. Launch of Innovative ADHD Treatment AZSTARYS™ (serdexmethylphenidate and dexmethylphenidate capsules) by Corium, Inc.  Kempharm to be added to Russell 2000 and 3000 indexes effective June 28, 2021.  Kempharm executives to participate in panel discussions during upcoming Jun e 2021 conference.  Kempharm announced that six U.S. patents governing serdexmethylphenidate (SDX), Kem Pharm ’ s prodrug of d - methylphenidate (d - MPH), and AZSTARYS ™, are now listed in the U.S. Food and Drug Administration (FDA) publication.  Kempharm reported its financial results for the first quarter ended March 31, 2021.

4. Disclaimer Notice: The information contained in this e - mail message and its attachments is intended solely for the use of the ind i- vidual(s) to whom it is addressed and may contain information that is the confidential information of Acorn Management Partners L.L.C. ("AMP") and its subsidiaries. The Information may be about comp anies in which A.M.P has or may receive compensation in the future. Any material in this message should be considered as ADVERTISMENT ONLY . Please consult with a certified finan- cial advisor before making any investment decisions. All information on th is report should be confirmed before making an invest- ment decision. Acorn Management Partners L.L.C. ("AMP") and its subsid iaries, and any affiliates and information providers make no implied or express warranties on the information provided. This is no t to be construed as a solicitation to buy or sell securities. As with any stock, the featured companies involve a high degree of risk and volatility, and all investors/advisors should know that t hey may lose a portion or all of their investment if they decide to purchase any stock. Acorn Management Partners L.L.C. ("AMP") , i ts affiliates, associates, relatives and anyone associated with in any manner reserves the right to either buy or sell shares in th e profiled company's stock. The Securities and Exchange Commission has compiled an extensive amount of information concerning investing, including the inherent risks involved. We encourage our readers to visit the SEC's websi te to acquire this important information. Safe Harbor Dis- closure: Acorn Management Partners L.L.C. ("AMP") website publications ma y contain or incorporate by reference "forward - looking statements, including certain information with respect to plans and strategies of the featured company. As such, any state- ments contained herein or incorporated herein by reference that are not statemen ts of historical fact may be deemed to be forward - looking statements. Without limiting the forgoing, the words "believe(s) ," "anticipate(s)," "plan(s)," "expect(s)," "project(s)" and similar expressions are intended to identify forward - looking statements. There are a number of important factors that could cau s e actual events or actual results of the Companies profiled herein to differ mater ially from these indicated by such forward - looking statements. Certain statements contained herein constitute forward - looking statements within the meaning of Section 27A of the S e- curities Act of 1933 and 21E of the Exchange Act of 1934. Such statemen ts include, without limitation, statements regarding busi- ness and financing, business trends, future operating revenues an d expenses. Although the Company believes that the statements are reasonable, it can give no assurances that such expectations will prove to be co rrect. Investors are cautioned that any forward looking statements made by the Company, or contained in any and/or all profile/resear ch reports, contain no guarantee of future performance, and that the actual result may differ materially from those set forth in the f orward - looking statements. Difference in results can be caused by various factors including, but not limited to, the Company's abili ty to be able to successfully complete planned funding agreements, to successfully market its products in competitive industries or to effectively implement its business plan or strategies. Any statements that express or involve discussions with respect to predictio ns, expectations, beliefs, plans, projections, objectives, goals, assumptions, or future events or performance are not statements of hi storical fact and may be "forward looking statements." Forward looking statements are based on expectations, estimates, and projections at the time the statements are made that involve a number of risks and uncertainties which could cause actual results or events to differ materially from those presently anticipated. Forward looking statements in this action may be identified through th e use of words such as "expects," "will," "anticipates, " "estimates," "believes," "may," or by statements indicating certain actions "may," "could," or "might" occur. We encourage our read- ers to invest carefully and review all forms of investments and rea d the investor information. More information please visit http:// www.sec.gov and/or (FINRA) at: http://www.FINRA.com. Readers can review all pu blic filings by companies at the SEC's EDGAR page. The FINRA has published information on how to invest carefully at its web site. “ Full Market Awareness ” A Professional Relations Company And Consulting Firm 678-736-5685 Contact: Brandon Bouysou Brandon@AcornManagementPartners.com Atlanta, Georgia Sarasota, Florida

3. Management Travis C. Mickle, Ph.D.—President, CEO, and Board C hairman; Co - Founder Dr. Mickle co - founded KemPharm Inc. in 2006 with the discovery of the company ’ s LAT ™ (Ligand Activated Therapy) prodrug technology. As President, Chief Executive Officer and Chairman of the Board he over sees KemPharm ’ s business and scientific strategy and is instrumental in the ongoing development of t he company ’ s pipeline of proprietary prodrugs. Prior to founding KemPharm, Dr. Mickle served as Director of Drug Discovery and CMC at New River Pharmaceuticals where he was the principal inventor of Vyvans e®, a prodrug of amphetamine for the treatment of attention deficit hyperactivity disorder (AD HD). Today, Vyvanse is the branded market share leader in the estimated $15 billion plus ADHD market. The succes s of Vyvanse along with a robust pipeline of prodrugs targeting ADHD, pain and thyroid dysfunctions, which Dr. Mickle was responsibl e for creating, led to New River Pharmaceuticals being acquired by Shire Pharmaceutica ls, PLC for $2.6 billion. During his career, Dr. Mickle has been granted 44 US patents, 21 EP (Europe) patents and has authored more than 100 patent applications US and worldwide, primarily focused on abuse - deterrent prodrugs in pain management and mental health, including multiple patents for prodrugs of hydrocodone and methyphendiate. R. LaDuane Clifton, CPA—Chief Financial Officer, Secretary and Treasurer As Chief Financial Officer, Secretary and Treasurer, Mr. Clifton is responsible for the c ompany ’ s financial, operating and compliance activities. Mr. Clifton brings to KemPharm significa nt public company experience, along with expertise in managed care contracting and strategic leadership covering operations, compliance, investor relations and business development. Prior to joining KemPharm, Mr. Clifton served as the Chie f Financial Officer, Secretary and Treasurer of The LGL Group, Inc., a publicly - held global producer of highly - engineered electronic components and services. Mr. Clifton also previously served as the Chief Financial Officer of a21, Inc., a publicly - held holding company with businesses in stock photography and the online retail and manufact ure of framed art, as well as a variety of finance, medical cost analysis, and managed care provider contracting roles with Aetna, Inc. Sven Guenther, Ph.D.—Executive Vice President, Research and Development As Executive Vice President of Research and Development, Dr. Guenther leads KemPharm ’ s research team and plays a central role in the advancement of the company ’ s pipeline of NME prodrugs and the development of new products that utilize KemPharm ’ s proprietary LAT ™ discovery technology to improve one or more of the attributes of approved drugs. Prior to joining KemPharm, Dr. Guenther served as a research scientist for New Ri ver Pharmaceuticals, where he was part of the development team for Vyvanse®. He is an i nventor on a number of patents and patent applications and author of several research papers. Christal M.M. Mickle—Vice President, Operations and Product Development; Co - Founder Ms. Mickle co - founded KemPharm Inc. in 2006 and has held a variety of positions at the company including V ice President and Group Leader, Secretary, Vice President of Corporate Affairs and her current posi tion as Vice President Operations and Product Development. Since KemPharm ’ s inception, Ms. Mickle has played an integral part in the start - up and ongoing growth and operations of the company. Today, as Vice President Operations and Product Development, Ms. Mickle oversees the development of each of KemPharm ’ s products through strategic collaboration across the various drug development disciplines including clinical, r egulatory, non - clinical, and manufacturing enabling efficient use of funds and the ability to meet timelines and milestones. Prior to founding KemPharm, she served as a Research Associate for New River Pharmaceuticals preparing c ompounds in the areas of ADHD, pain, and thyroid dysfunctions for further study. Ms. Mickle received her M.A. degree from the University of Virginia and her B.A. and B.S. degrees from Virginia Polytechnic Institute and State University. www.kempharm.com

1. A C O R N M A N A G E M E N T P A R T N E R S , L L C Pharmaceuticals Technology For More Information: “ Call AMP ” Brandon Bouysou 678 - 736 - 5685 KemPharm.com KemPharm Inc. (NASD: KMPH) is a clinical - stage specialty pharmaceutical company engaged in the discovery and development of proprietary prodrugs that are designed to be improved versions of widely prescribed and FDA approved drugs. KemPharm has employed its LAT ™ technology to create a diverse pipeline of prodrug therapeutics that target large market opportunities in pain, attention deficit hyperactivity disorder (ADHD) and other central nervous system indications. KemPharm has already received FDA approval for its prodrug product, APADAZ®. LAT ™ Technology KemPharm ’ s strategy is to employ its LAT ™ (Ligand Activated Therapy) technology to discover and develop prodrugs that are new molecules that can improve one or more of the attributes of approved drugs, such as susceptibility to abuse, bioavailability and safety. Elegant in design and utilization, the LAT ™ technology has been proven effective for over a decade in numerous clinical and preclinical trials. LAT ™ technology has demonstrated the ability to improve the attributes of approved drugs and allows the company to develop prodrugs that may be eligible to use the 505(b)(2) NDA pathway. Additionally, the ligands typically used have been demonstrated to be safe in toxicological studies or have been granted Generally Recognized as Safe (GRAS) status by the FDA. KemPharm continues to employ its LAT ™ technology to create a portfolio of product candidates that potentially offer significant improvements over FDA - approved and widely prescribed drugs. Company Highlights  Product License Agreements— Under the terms of the amended License Agreement, KemPharm is now eligible to receive a total of up to $590 million in future regulatory and sales milestone payments for AZSTARYS, as well as tiered royalty payments on a product - by - product basis for net sales. Royalty rates range, on a product - by - product basis, from a percentage in the high single digits up to the mid - twenties for U.S. net sales, and a percentage in the low to mid - single digits of net sales in each country outside of the U.S.  Product Pipeline Expectations— On May 7, 2021 Kempharm announced that serdexmethylphenidate (SDX), KemPharm ’ s proprietary prodrug of d - methylphenidate (d - MPH) and the primary active pharmaceutical ingredient (API) in AZSTARYS ™, has been classified as a Schedule IV controlled substance by the U.S. Drug Enforcement Administration (DEA). Per the License Agreement, as amended, with an affiliate of Gurnet Point Capital (GPC), KemPharm has earned a $10 million milestone payment which is payable within 30 days following the scheduling determination of SDX by the DEA.  Financial Position —The successful completion of this series of transactions, culminating in aggregate gross proceeds of approximately $94 million, has allowed the Company to regain its listing on The Nasdaq Capital Market, created the opportunity to eliminate all of the Company ’ s debt, and has provided a substantial amount of new capital to propel the Company ’ s efforts to create shareholder value.  LAT ™ Technology— Applicable across many therapeutic areas and already proven to produce and improve FDA - approved products. AMP Quick Facts KemPharm Inc. (NASD: KMPH) August 2 0 2 1 NASD: KMPH Price: $ 10.00 8 / 02 /21 Fiscal Yr: 12/31 Market Cap: $ 350.46 Cash on Hand: $ 120M Revenue: $ 12.1M Shares Out: 33.89M Float: ~ 2 5M Avg Volume: 830,000 Employees: 22

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